Latest news from the Beatty Research Group.
Our recent VIPER paper (PNAS, 2018) was selected by OHSU's School of Medicine as the paper of the month! Click here to read about it.
There is a lot of great color chemistry happening in the Beatty lab and in the next two modules (Strongin and Gibbs). Inspired by that, Dr. Beatty produced some melted crayon art. If you are in the RLSB in Portland, OR, stop by to see it!
The Beatty lab homepage now features an updated banner, which is designed to highlight our work at the interface of chemistry and biology. The images were collected by graduate students in the group (Katie and Julia), and highlight our research on esterases in M. tuberculosis, development of genetically-encoded tags (e.g., VIPER), and imaging the iron uptake machinery.
The Beatty lab is grateful to NIGMS for funding an equipment grant supporting the purchase of a multi-modal Amersham Typhoon. This instrument will be used to image VIP tags and for assessing interactions between our fluorescent probe peptides and their targets.
The Beatty lab celebrated the new PNAS publication with a celebration on Dec. 14. We included lab alums Sam Levine, Jon White, and Katie Tallman. Dr. Beatty made a pavlova with raspberries and lemon curd. It was a lot of fun to get the group together and to end the year on a high note. We took a picture after Savannah, Caroline, Dan, and Claudia left:
We recently published new work in PNAS, "VIPER is a genetically encoded peptide tag for fluorescence and electron microscopy." This project describes our latest peptide tag, VIPER, which can be used to tag and track cellular proteins across microscopy platforms. Great job Team VIP!
The Beatty lab is happy to welcome Savannah Tobin to Team VIP. Savannah is a recent UC Davis graduate, where she completed her B.S. in the Biological Sciences. Savannah was previously a member of the Albeck Lab (UC Davis), where she worked closely with Alexander Davies on cancer signaling. She has also worked on projects in veterinary genetics, examining feline coat color patterns and the Fed d1 allergen.
Kimberly Beatty prepared a last-minute halloween costume, celebrating the VIP tag technology. Finley let her borrow the reporter chemistry for the day.
Kimberly Beatty and Michael Pluth (UO) co-organized the first-ever Oregon Translational Chemical Biology (OCTB) symposium at OHSU on October 30. Over 150 people attended this event, which was open to OHSU and UO. The event was designed to bring together chemical tool "makers" and tool "users". A day of great talks was followed by a poster session and reception. Speakers included Darren Johnson, Carsten Schultz, Brian Druker, Gordon Mills, Summer Gibbs, Francis Valiyaveetil, and others.
Julia Doh and Kimberly Beatty attended ProbeFest 2018 at Janelia Research Campus. This meeting was organized by Luke Lavis, Martin Schnerman, and Elizabeth New. Kimberly gave a talk on the VIP tags ("A new technology for tracking cellular proteins at high resolution") and chaired a session ("Session 4: Click It"). Julia presented a poster on her recent CLEM work.
Julia provided the photo of the Janelia lake and the following summary of the meeting, "At Janelia I loved how much artwork was displayed throughout the entire campus. It made me want to get some of my research professionally printed. Probefest was the best conference I had ever attended. The small size and organization made it very easy to befriend other researchers and approach professors. The talks were all very well done, however the final day of talks was my favorite, highlighting new discoveries with some very complex imaging. My favorite talks from Janelia were given by Erik Jorgensen, Kai Johnsson, Daniel Choquet, Michael VanNieuwenhze and Josh Vaughan."
Julia Doh and Kimberly Beatty attended the WMIC meeting in Seattle, Washington. Kimberly gave a talk and Julia presented a poster.
Julia provided this comment about the meeting: "At WMIC one of the things I enjoyed the most about the conference was meeting so many research groups from different countries at the poster session. My poster was assigned next to Japanese graduate students at RIKEN who were validating probes for clinical use in MRI. My favorite research presented was the acoustic/MRI reporter genes from Mikhail Shapiro's lab. I saw his student speak during one of the sessions and Dr. Shapiro gave the Roger Tsien Memorial Lecture at the end of the conference."
Congratulations to Jon White! Jon has joined the faculty at Longwood University as an assistant professor of chemistry and biochemistry. He was a postdoc in the Beatty lab from 2015-2017 and completed his PhD at University of Oregon. Good luck Jon!
Dr. Beatty volunteered on June 24 at a "STEM Like a Girl" workshop in Portland, Oregon. The program was organized by STEM Like a Girl (http://stemlikeagirl.org/), and was offered to 3rd to 6th grade girls and their parents. Dr. Beatty helped the girls make fizzy flower bath bombs, which used acid-base chemistry. They also had the chance to make an art robot, a really fun challenge that involved a lot of trial and error. The girls were enthusiastic to learn about opportunities to become scientists, and the event was a lot of fun!
Dr. Beatty was featured on the STEM Like a Girl blog.